Can character concepts be hand drawn?

Or do they have to be anime related.

Hand drawn is perfectly fine as long as you're clear as to what you want. I'm a little confused when you ask if they have to be anime related. Since DDs are dolls that look like anime characters then yes your hand drawn character should look anime-ish for best results but if you mean the character must come directly from an anime then nope. ...hope that makes sense. Lol

it can be your own original designs, if that is what you are asking?